Adipose Derived Stem CellsWhat are Stem Cells?
Stem cells have regenerative potential to develop into muscle, tendon, bone, or cartilage that replenish the dead or dying cells in injured site.
Features of Stem Cells
- High proliferative capacity
- Possibility of self-maintenance
- Ability to generate differentiated progenitors
Adipose Derived Stem Cells
- Adipose tissue is composed of 3 elements
- Mature Adipose cells
- Adipose Derived Stem Cells (ADSC)
- Stromal-Vascular Cells (SVF)
- Immune cells
- pericytes
- Progenitor cells
- Stromal cells
Adipose Derived Stem Cells
What is their importance?
- ADSC differentiate to mature adipocytes and fibroblasts cells.
- Pericytes differentiate and become mesenchymal stem cells
- SVF aid tissue regeneration and stimulate neoangiogenesis.
- SVF release high concentration of GrowthFactors
- SVF contribute to dermal tissue reconstruction
Therapeutic Applications
Osteochondral lesions
Avascular necrosis
Spinal fusion
Traumatic bone loss
